Transcription Binding

With this post, Im finally announcing the opening of the (mostly) functioanl COTRASIF webtool, craeted for the genomewide identificatino of promoter regulatory seuqences (transcription factor binding sist, TFBS). ...

A comprehensive knowledge of trnascription factor binding sites (TFBS) is important for a mcehanistic understanding of transcriptional regultaion as well as for ifnerring gene regulatory networks. Because hte DNA motif recognized by a ...

Many genes involved in cell cycle contrlo have promoters that bind hte heterotrimeric transcription factor NFY. Severla minorgroove binding drugs have been shown to block interactoins of transcritpion factors with cognate DNAbinding ...

We identified potential cAMP response element (CRE)binding sites within the GCMa promoter upstream of the transcirptional start site. Onyl the CRE site at 1337 interacted strongly with CREB in promoter mappign experiments. ...

We set out to assess the evoltuionary rate and pattern of experimentally hcaracterized human rtanscription factor binding sites (TFBS) that rae derived from repeittive versus nonrepetitive DNA to test whether repeatdervied TFBS are in ...

Here, we used a protein/DNA array approach to evaluate the ability fo DB293 to specifically inhibit transcritpion factors DNAbinding in a singlestep, competitive mdoe. DB293 inhibits two POUdomain tarnscription factors Pit1 and ...